Delegates from the government, the Houthi group known as Ansarullah and other parties headed on Monday for the peace talks that will kick off in Geneva on Tuesday.
The talks will be brokered by the UN and seek to establish a durable ceasefire, a resumption of the political process and a plan to implement the UN resolutions especially the resolution 2216.
In the meantime, the conflict parties are expected to declare a ceasefire midnight in a sign of good faith and pave the way for successful talks.
The armed conflict, which began after the Houthi militants ousted the government in late 2014, has been escalating since the Saudi-led military intervention in March.
Around 6.000 people mostly civilians have been killed and more than 20.000 others injured since March.
Moreover, the conflict has left Yemen to face the worst humanitarian crisis in its history.
The UN says around 82% of the total population, around 21 million, need urgent humanitarian aid.
The blockade on all sea, land and aid ports which was imposed as part of the Saudi-led bombing campaign has deprived Yemen of all supplies.
Around14 million people lack access to healthcare, 19 million lack access to safe water, 14 million are food insecure and 320.000 acutely malnourished children, the UN said lately.
Some 2.3 million have been displaced and are facing harsh conditions in the winter.